A Review on Synthesis of new Azo Compounds of Para Hydroxy Benzaldehyde and Determination of their Activity

Abstract

This study aims to prepare some azo compounds by diazo coupling reaction of aromatic amines with Para hydroxy benzaldehyde. Azo dyes are Compounds containing in their structure a group or more of the AZO groups (–N=N–) called azo compounds, in which the nitrogen atom hybridization is sp 2 . azo's properties entirely depend on the structure of the compound, the number of azo linkages, and both groups on each end of the -N=N- linkage. The prepared compounds then identified using FT-IR spectroscopy. The purity of the dye was checked by thin layer chromatography(TLC) using solvent system and melting point. The results supported the structure of concerned compounds. Finally The synthesized azo compounds were screened in vitro for their biological activity as antibacterial agents against: Staphylococcus aureus, Esherichia Coli, Klebsiella pneumonia and Pseudomonas aerug inosa

Key Words: Benzaldehyde, chromatography, Esherichia Coli, Hybridization, Staphylococcus aureus