Oro dispersible Films: Recent Trends and Formulation Techniques

Abstract

Oro dispersible films (ODFs) are an innovative oral drug delivery system designed to rapidly disintegrate and dissolve in the oral cavity without the need for water. Offering improved patient compliance, especially among paediatric, geriatric, and dysphagic populations, ODFs have gained considerable attention in recent pharmaceutical research. This project explores the fundamental concepts of or dispersible films, focusing on their composition, formulation techniques, evaluation parameters, and recent advancements. Key advantages such as ease of administration, faster onset of action, and enhanced bioavailability are discussed, alongside limitations like drug loading capacity and stability concerns. A detailed literature review highlights previous research trends and market-approved ODF formulations. The study also outlines formulation methodologies involving solvent casting, hot-melt extrusion, and electrospinning, backed by analytical evaluation techniques. Overall, the project emphasizes the growing relevance and potential of ODFs in the development of patient-centric drug delivery solutions.

Keywords: Oro dispersible films, drug delivery, solvent casting, patient compliance, formulation techniques, rapid disintegration