Formulation and Evaluation of Herbal Immunity Booster Tablets

Abstract

The increasing global interest in natural remedies and preventive healthcare has accelerated the development of herbal formulations aimed at enhancing the immune system. This study focuses on the formulation and comprehensive evaluation of herbal immunity booster tablets, utilizing traditionally recognized medicinal plants with scientifically established immunomodulatory, antioxidant, and anti-inflammatory properties.

The formulation incorporates key herbs including Ocimum sanctum (Tulsi), Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy), Emblica officinalis (Amla), and Curcuma longa (Turmeric). These herbs were selected based on Ayurvedic literature, ethnopharmacological evidence, and modern scientific data supporting their role in modulating immune responses and protecting against infections and oxidative stress.

The powdered plant materials were subjected to standardization and quality control tests before being formulated into tablets using the direct compression method. Pre-formulation studies included analysis of flow properties such as angle of repose, bulk and tapped density, and Carr’s Index. Post-compression evaluation involved tests for tablet hardness, thickness, friability, disintegration time, weight variation, and uniformity of content, all of which conformed to pharmacopeial standards.

In addition, phytochemical screening confirmed the presence of bioactive compounds such as flavonoids, alkaloids, tannins, glycosides, and polyphenols. The tablets were also evaluated for in-vitro antioxidant activity using the DPPH assay and for anti-inflammatory potential using protein denaturation methods. Results revealed that the tablets possessed significant biological activity, indicating their potential to reduce oxidative damage and modulate immune function.

Further work such as accelerated stability testing, clinical evaluation, and toxicological studies is recommended to validate the safety and long-term efficacy of the formulation.

Keywords: Herbal formulation, Immunity booster, Immunomodulatory activity, Antioxidant properties, Anti-inflammatory effects, Ayurvedic herbs, Phytochemical analysis