AN IN VITRO ANTIMICROBIAL POTENTIAL OF VARIOUS EXTRACTS OF COMMIPHORA MYRRHA

  • Abd-Ulgadir K S1; El Tahir A S2;AhmedH H2;El Shiekh H E2;Rakaz M A2;Abosalif KO Abdelsalam KA4; Satti AB3 1 Department of Microbiology, Faculty of Nursing Science, OIU. 2 Department of Botany, Faculty of Science and Technology, OIU. 3 Department of Medical Parasitology & Medical Entomology, Faculty of Medical Laboratory Science, OIU. 4 College of Applied Medical Sciences, Shaqra University - KSA.

Abstract

Objectives: The aim of this study was to evaluate the antimicrobial activity of various extracts of the medicinal plant Commiphora myrrha. Methods: The agar well diffusion technique was followed to perform the antimicrobial activity of the candidate extracts against Gram- positive bacteria (Bacillus subtilis, Staphylococcus aureus), Gram- negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa), and two fungal species (Candida albicans, Apergillus Niger). Results: Methanolic and aqueous extracts of the resin of Commiphora myrrhaat concentration of 100 mg/ml was found to be more active against Gram- negative bacteria (Proteus vulgaris; Klebsiella pneumoniae; Escherichia coli and Pseudomonas aeruginosa) and Gram- positive bacteria (Bacillus subitilis), and also showed high antifungal activity against (Candida albicans and Aspergillus niger). While chloroform extract of the resin showed moderate activity towards Gram- positive and Gram- negative bacteria ,as well as against Candida albicans, whereas the same extract revealed high antifungal activity against Apergillus Niger. Conclusion: Methanolic, chloroform and aqueous extracts of Commiphora myrrha resin revealed that the selected entire plant had a significant potential effect capable to inhibit the growth of both bacterial and fungal standard species. Keywords: Commiphora myrrha, antimicrobial activity, methanol extract, chloroform extract, standard strains.

Published
2015-04-30
How to Cite
Abdelsalam KA4; Satti AB3A.-U. K. S. E. T. A. S. H. S. H. E. M. A. K. (2015). AN IN VITRO ANTIMICROBIAL POTENTIAL OF VARIOUS EXTRACTS OF COMMIPHORA MYRRHA. Journal of Biomedical and Pharmaceutical Research, 4(2). Retrieved from http://jbpr.in/index.php/jbpr/article/view/178
Issue
Vol. 4 No. 2 (2015)
Section
Research Articles

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