EVALUATION OF PLATELET COUNT AND PLATELET INDICES IN PATIENTS WITH ACUTE MALARIA IN SHENDI LOCALITY

  • Mohamed Abdelrahamn1, Elfatih Mohammed2, Abdelwahab Abdien3, Rashid Eltayeb4, Mohammed Osman5 1Mohamed. S, PSC Medical Laboratory Science, Shendi University, Haematology Department. Shendi 2Elfatih. A, MSC Medical Laboratory Science, Shendi University, Haematology Department. Shendi 3Abdelwahab. S, MSC Medical Laboratory Sciences, Shendi University, Clinical Chemistry Department. Shendi 4Rashid. E, MSC Medical Laboratory Sciences, Shendi University, Haematology Department. Shendi 5Mohammed. A, MSC Medical Laboratory Sciences, Shendi University, Haematology Department. Shendi

Abstract

Background: Malaria is the commonest cause of morbidity in Africa.  This study describes altered platelet count and platelet indices in patients with acute malaria caused by Plasmodium falciparum, Plasmodium vivax and plasmodium malariae and uses these alterations as initial hint for malarial infection and therefore encourage the laboratory physicians for more depth search of the parasite microscopically. Methods: Platelet count and platelet indices in (123) patients with acute malaria were evaluated, living in Shendi locality in northern Sudan, an area of malarial holoendemic transmission. Results: The results of this study showed that platelet count, mean platelet volume (MPV), and Plateletcrit (PCT) values were exhibited significant decrease, but there was no change in platelet distribution width (PDW). Three sympatric Plasmodium species were recorded during this study with different prevalence of (77.2%) P.falciparum, (13.8%) P.malairae and (8.9%) P.vivax consequently. Mean platelet count decreased with an increase in density of parasitaemia. Conclusion: Malaria is associated with different degrees of reduction platelet count and alteration of platelet indices and may be used as probable indicator for malaria in endemic regions and therefore encourage the laboratory physicians for more depth search of the parasite microscopically.

Keywords: Malaria, Plasmodium species, Platelets.

Published
2014-06-28
How to Cite
Mohammed Osman5M. A. E. M. A. A. R. E. (2014). EVALUATION OF PLATELET COUNT AND PLATELET INDICES IN PATIENTS WITH ACUTE MALARIA IN SHENDI LOCALITY. Journal of Biomedical and Pharmaceutical Research, 3(3). Retrieved from http://jbpr.in/index.php/jbpr/article/view/265
Section
Research Articles