DETECTION OF EPSTEIN - BARR VIRUS IN LYMPHOMA LESIONS AMONG SUDANESE PATIENTS USING LMP-1 MONOCLONAL ANTIBODY

  • Marwa Salah Abdalla Abdelmageed1, Esam Mohamed Abdulraheem2, Babikir Ishag Mohamed Fadul3 1Department of Histopathology and Cytology, Neelain University, Khartoum, Sudan. E. mail: marwaf_2014@hotmail.com 2Department of Medical Laboratories, College of Applied Medical Science, Shaqra University, Saudi Arabia. E. mail: esamcytomed@yahoo.com 3National Health Laboratory, Ministry of Health, Khartoum, Sudan. E. mail: babikirf@gmail.com

Abstract

OBJECTIVE: this was a retrospective descriptive study aimed to investigate the association of EBV with different types of lymphoma in Sudanese patients.

METHODS: Fifty paraffin-embedded formalin-fixed tissue sections of lymphoma lesions were immunohistochemically stained using latent membrane protein-1 (LMP-1) Monoclonal Antibody and results were analyzed using SPSS version 16.

RESULTS: Only two cases were positive for EBV LMP-1, one was NHL B cell type and the other was Hodgkin’s Lymphoma.

CONCLUSION: the results do not support considering EBV LMP 1 as a significant prognostic factor for lymphoma in our locality.

KEY WORDS: EBV, LMP-1, Lymphoma, Sudan

Published
2014-12-30
How to Cite
Babikir Ishag Mohamed Fadul3M. S. A. A. E. M. A. (2014). DETECTION OF EPSTEIN - BARR VIRUS IN LYMPHOMA LESIONS AMONG SUDANESE PATIENTS USING LMP-1 MONOCLONAL ANTIBODY. Journal of Biomedical and Pharmaceutical Research, 3(6). Retrieved from http://jbpr.in/index.php/jbpr/article/view/329
Issue
Vol. 3 No. 6 (2014)
Section
Research Articles

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