BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA

  • Mostafa M. Saleh1, Mohammed M. Ghoneim1, Saeid Kottb1, Atef A. El-Hela1* aDepartment of Pharmacognosy, Faculty of Pharmacy, The University of Al-Azhar, Cairo 11371, Egypt.

Abstract

Phytochemical study of the ethanolic extract of Kalanchoe tomentosa  (Crassulaceae)  resulted in the isolation of 14 compounds identified as; α-amyrin acetate (1), friedelin (2), glutinol (3), 1-dotriacontanol (4), phytol (5), Stigmasta-7,25-dien-3b-ol (6), β-sitosterol (7), Isorhamnetin (8), 2,3-dihydroxypropyl tetradecanoate (9), Eriodictyol (10), Gallic acid (11), quercetin (12), kampferol-3-O-Rutinoside (13) and isovitexin (14). These compounds were isolated for the first time from this species. The structure elucidation of isolated metabolites was carried out using spectroscopic data (1D and 2D NMR). Antioxidant, cytotoxic and antimicrobial activities of different plant extracts were also studied and significant results were obtained.

Key words:Kalanchoetomentosa; Crassulaceae; cytotoxicity and antimicrobial activities.

Published
2014-12-30
How to Cite
Saeid Kottb1, Atef A. El-Hela1*M. M. S. M. M. G. (2014). BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA. Journal of Biomedical and Pharmaceutical Research, 3(6). Retrieved from http://jbpr.in/index.php/jbpr/article/view/332
Issue
Vol. 3 No. 6 (2014)
Section
Research Articles

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