Seroprevalence of Herpes Simplex Virus (HSV-1 and HSV-2) Infections in Sudanese Renal Transplant Recipients

Authors

  • Shaza Abd Allah AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology
  • Mustafa E M Yassin AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology
  • Khalid Abdalmoniem AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology
  • Khalid A. Enan AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology
  • Mohammed Nafi AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology
  • Isam M Elkhidir AL-Neelain University, Faculty of Medical laboratory Science; Department of Microbiology

Abstract

Introduction: Viruses are among the most common causes of opportunistic infections after transplantation, because of their immunocompromised condition.

Aim: This study aimed to determine Herpes Simplex Virus-1 and Herpes Simplex Virus-2 (HSV-1 and 2) seropositivity among Sudanese kidney transplant recipients.

Material and Methods: One hundred eighty four serum samples of 92 Sudanese Kidney transplant recipients and 92 control group (blood donors) were tested serologically to detect HSV-1 and HSV-2 IgG and IgM antibodies using an enzyme-linked immunosorbent assay.

Results: The HSV1/2 IgG was positive in 99% of the renal transplant recipients, while HSV1/2 IgM was positive in 50% of renal transplant recipients. In control group, HSV1/2 IgG was positive in 90% while HSV1/2 IgM was positive in 6%. For HSV1/2 IgG and HSV1/2 IgM Seroprevalence was higher in females (100%, 53%) compared with males (94%, 25%). There was association between HSV seropositivity and age (P<0.001).

Conclusions: The Seroprevalence of HSV-1 and HSV-2 among study kidney transplant recipients was high (99%, 50% for HSV 1-2 IgG and IgM antibody respectively), so this viral infection must be remains in concern.

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Published

2013-10-30

How to Cite

Shaza Abd Allah, Mustafa E M Yassin, Khalid Abdalmoniem, Khalid A. Enan, Mohammed Nafi, & Isam M Elkhidir. (2013). Seroprevalence of Herpes Simplex Virus (HSV-1 and HSV-2) Infections in Sudanese Renal Transplant Recipients. Journal of Biomedical and Pharmaceutical Research, 2(5). Retrieved from http://jbpr.in/index.php/jbpr/article/view/783

Issue

Vol. 2 No. 5 (2013)

Section

Research Articles

License

Creative Commons LicenseJournal of Biomedical and Pharmaceutical Research by Articles is licensed under a Creative Commons Attribution 4.0 International License.