Journal of Biomedical and Pharmaceutical Research http://jbpr.in/index.php/jbpr <p>&nbsp; &nbsp; &nbsp;<img src="/public/site/images/adminjbpr/nlm.jpg" width="219" height="144">&nbsp; &nbsp; &nbsp; &nbsp;<img src="/public/site/images/adminjbpr/www.jbpr_.in_.jpg">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;<img src="/public/site/images/adminjbpr/DOI.png" width="221" height="144"></p> <p>&nbsp;</p> <p>&nbsp; &nbsp; &nbsp;&nbsp;<a title="|| Pub-Med NLM ID (URL) ||" href="https://www.ncbi.nlm.nih.gov/nlmcatalog/101671502" target="_blank" rel="alternate noopener noreferrer">|| Pub-Med NLM ID (URL) ||</a>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;<a href="https://journals.indexcopernicus.com/search/details?id=40734" target="_blank" rel="alternate noopener noreferrer">|| Index Copernicus (URL) ||</a>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;<a href="https://journals.indexcopernicus.com/search/details?id=40734" target="_blank" rel="alternate noopener noreferrer">||</a><strong>CrossRef DOI: 10.22270/JBPR.jbpr.in<a href="https://journals.indexcopernicus.com/search/details?id=40734" target="_blank" rel="alternate noopener noreferrer">||</a></strong></p> <p>&nbsp; &nbsp; &nbsp; &nbsp;</p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><span style="text-align: justify;">Journal of Biomedical and Pharmaceutical Research (JBPR) is an international, peer-reviewed, open access, online journal dedicated to the rapid publication of full-length original research papers, short communications, invited reviews, Case studies and editorial commentary and news, Opinions &amp; Perspectives and Book Reviews written at the invitation of the Editor in all areas of the Biomedical and Pharmaceutical Sciences.</span></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Medical || Dentistry || Biomedical Sciences&nbsp;|| Ayurveda&nbsp;|| Homeopathy&nbsp;||&nbsp;</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Anatomy, Physiology, Biochemistry, Molecular Biology, Cell biology, Genetics, Hematology, Pathology, Immunology, Microbiology, Virology, Parasitology, Surgery, Dental Sciences, Sports Physiology,&nbsp;Histopathology, Toxicology and all major disciplines of Biomedical Sciences.<br> <strong>Pharmaceutical Sciences || Allied Sciences&nbsp;</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Toxicology, Pharmaceutical and Biomedical Analysis, Clinical Research, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology and all major disciplines of Pharmaceutical&nbsp; Sciences.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Articles are published as they are accepted and are freely available on the journal’s website to facilitate rapid and broad dissemination of research findings to a global audience.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Top Reasons for publication with us</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Quick Quality Review:</strong> The journal has strong international team of editors and reviewers, Rapid Decision and Publication</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Very Low Publication Fees:</strong> Comparable journals charge a huge sum for each accepted manuscript. JPBR only charge the fees necessary to recoup cost associated with running the journal</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Other features:</strong> DIDS Assigned and Implemented the Open Review System (ORS).</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Important Notice:</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Author can now directly send their manuscript as an email attachment to</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Innovative Library</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>editor@jbpr.in</strong>, <strong>drpriyankagupta6@gmail.com</strong></span></span></p> <p>&nbsp;</p> Innovative Library en-US Journal of Biomedical and Pharmaceutical Research 2589-8752 <p><a href="http://creativecommons.org/licenses/by/4.0/" rel="license"><img style="border-width: 0;" src="http://i.creativecommons.org/l/by/4.0/88x31.png" alt="Creative Commons License" width="60" height="21" border="0"></a><span style="line-height: 1.3em;">Journal of Biomedical and Pharmaceutical Research&nbsp;</span><span style="line-height: 1.3em;">by </span><span style="line-height: 1.3em;">Articles</span><span style="line-height: 1.3em;"> is licensed under a </span><a style="line-height: 1.3em;" title="Journal of Biomedical and Pharmaceutical Research" href="http://creativecommons.org/licenses/by/4.0/" target="_blank" rel="license noopener">Creative Commons Attribution 4.0 International License</a><span style="line-height: 1.3em;">.</span></p> OCCLUSION THERAPY TREATMENT IN AMBLYOPIC EYE http://jbpr.in/index.php/jbpr/article/view/528 <p>“Amblyopia is the most common visual disorder of childhood, yet the contributions of the two principal treatments (spectacle wear and occlusion) to outcome are unknown. The MOTAS study investigated the dose-response relationship between occlusion (patching) and improvement in visual acuity. The use of the Occlusion Dose Monitor (ODM) to record the amount of occlusion dose received by the child represents a major innovation and is unique to these study.The most common causes of visual impairment in adults and children, and visual loss may be permanent if not treated in time. Though many studies have been done on occlusion therapy which is the mainstay in the treatment of unilateral amblyopia, discrepancies exist in literature about quantification of treatment and follow up measures. The present study was undertaken to evaluate the factors responsible for the successful outcome of treatment and the optimum time required for the same in children with unilateral amblyopia.Baseline characteristics of 60 verbal patients with unilateral amblyopia (strabismic, anisometropic, mixed) referred to the Strabismus and Amblyopia Clinic at the Dr. NimeshMathur Centre for Ophthalmic Sciences,Navi Mumbai between September 2016 to December 2017 who improved to the desired level of visual acuity after treatment for amblyopia in the mentioned time period, were analyzed to assess for factors that directly or indirectly influenced the optimum visual rehabilitation and the average duration of therapy required for the same. The evaluation included assessment of the baseline best-corrected visual acuity (BCVA) and refractive status in both eyes, the age at presentation, the type of amblyopia present, fixation pattern in the amblyopic eye, intereye visual acuity difference, and evaluation of compliance through a parental diary system.BCVA in the amblyopic eye was similar in all the three groups. Patients with anisometropicamblyopia showed a quicker response to therapy. Compliance to treatment was the major factor affecting the overall time required for a successful outcome in most cases.</p> Dhiraj Kumar Verma ##submission.copyrightStatement## 2018-05-09 2018-05-09 7 03 EFFECT OF LACTATE DEHYDROGENASE (LDH) IN PREECLAMPSIA OF PREGANANY http://jbpr.in/index.php/jbpr/article/view/529 <p>Preeclampsia is responsible for significant maternal and perinatal mortality worldwide. Lactate dehydrogenase (LDH) is a multifaceted enzyme whose effects in pregnancy related complications e.g., preeclampsia (PE) is now gaining attention. Here we present evidence that LDH levels could contribute significantly to the outcomes of PE Lactate dehydrogenase is mainly an intracellular enzyme. The levels of LDH in serum are increased in clinical situations associated with cell damage, leak, and hemolysis and cell death. Preeclampsia is such a situation associated with these features. The present study was done to know the levels of serum LDH in preeclampsia patients and if there is an association between these LDH levels and the fetal outcome. A case control study was done with 100 pregnant women diagnosed with preeclampsia and 50 pregnant women without any complications as controls. LDH levels were found to be higher in preeclampsia patients compared to controls. The fetal outcome was poor in the group having high LDH levels. Levels of lactate dehydrogenase as a biochemical marker are easily available test which can be offered to all patients with Hypertension. LDH Levels can be used as a biochemical predicator for the prognosis of preeclampsia.</p> <p><strong>Keywords:&nbsp;</strong>Pregnant women, Preeclampsia, lactate dehydrogenase, LDH.</p> Savita Kumari Diksha Mishra ##submission.copyrightStatement## 2018-05-09 2018-05-09 7 03 Concentrated Growth Factor - Review http://jbpr.in/index.php/jbpr/article/view/534 <p>Regenerative medicine is one of the most dominant objectives of today’s rehabilitation therapies. Growth factors are bioactive proteins which control the process of wound healing. Platelet concentrates are rich in growth factors enhancing wound healing process and promotes regeneration of bone. One such platelets concentrates is Platelet Rich Fibrin (PRF) a second generation platelet derivative used widely for bone healing. And in 2006 Sacco introduced advanced second generation platelet derivative Concentrated Growth Factor (CGF), which showed enhanced bone healing capacity, higher tensile strength; more growth factors, higher viscosity and higher adhesive strength than PRF . Recently more importance has been given to CGF for its excellent biological activity and predictable method of preparation, their by findings its way in the field of regeneration.</p> <p><strong>Key words:</strong> Concentrated Growth Factors, Platelet Rich Fibrin, regeneration, growth factors.</p> Prof.Dr.M. Kavitha Dr.S. Kathiravan ##submission.copyrightStatement## 2018-05-09 2018-05-09 7 03