A REVIEW ON THE RECENT INNOVATIONS IN TRANSDERMAL DRUG DELIVERY FOR HERBAL THERAPY

Swati Hardainiyan1, *Bankim C. Nandy2, Nakuleshwar Dut Jasuja1, Pritesh Vyas1, Pramod K Raghav1

Swati Hardainiyan1, *Bankim C. Nandy2, Nakuleshwar Dut Jasuja1, Pritesh Vyas1, Pramod K Raghav1 1Department of Biotechnology and Food Sciences, 2Department of Pharmaceutical Science, Jayoti Vidyapeeth Women’s University, Jaipur - 303122, Rajasthan, India.

Abstract

This review focuses on the recent innovation in Transdermal drug delivery system which can be a stand for the research and development of pharmaceutical dosage form for transdermal drug delivery. TDDS (transdermal drug delivery system) improve beneficial value and drug safety by further site definite the way and temporal position in the body’s vital to reduce the number and size of doses necessary to achieve the objective of systemic medication through topical application to the intact skin surface. TDDS has abundant advantages more than usual drug delivery route. Transdermal route or therapy is non-invasive that includes lack of first pass metabolism effect, high bioavailability and steady drug plasma concentration. A Transdermal Patch is an adhesive patch that has a coating of medicine (drug) that is placed on the skin to deliver specific dose of the medicine (drug) into the bloodstream over a period of time. The present review focused on the delivery of some herbal agents through transdermal route. The main principle of developing unconventional drug delivery technologies is to offer more convenience for patients and increase the effectiveness and protection of drug. The aim of the present review at formulation of transdermal patches incorporating herbal drug components. Transdermal patch is a medicated adhesive pad that is designed to release the active ingredient at a constant rate over a period of several hours to days after application to the skin. It has been found that drugs from herbal origin can be utilized with enhanced efficacy by incorporating in transdermal drug patches. Herbal transdermal patches which aids to quit smoking, relieve stress, increase sexuality, insect repellant patches, detoxification, male energizer, postpone menopause are available. The objective and aim of the transdermal drug delivery system is topically administered drug in the form of patches that is delivering the drug in the body through the skin for systemic effect at a predetermined time period.

Key words: Transdermal Patch, Herbal Therapy, Polymers, Medicine.