THE IMPACT OF TRANEXAMIC ACID ON POSTPARTUM BLOOD LOSS

Abstract

Introduction: Worldwide, postpartum haemorrhage (PPH) is a leading factor in maternal morbidity and mortality. Despite being a natural function, labour is frequently linked to morbidity and mortality. The most frequent cause of maternal death is bleeding. Blood loss of 500 mL or more after birth within 24 hours is known as postpartum haemorrhage.

Materials and Methods: In this observational study, 150 singleton pregnant women were randomly assigned to receive 10 units of oxytocin after foetus delivery, 1 gramme of intravenous tranexamic acid, or nothing at all. Using a graduated blood bag, quantify blood loss. Hematocrit and haemoglobin levels are measured before and after birth.

Results: When compared to the control group, the study group saw considerably less mean blood loss (245 ml vs. 327 ml, p=0.01). Hematocrit and haemoglobin levels after delivery were considerably lower in the study group when compared to the control group (11.4 gm/dl, 35% versus 10.5 gm/dl, 32%, p0.01).

Conclusions: Tranexamic acid aids in minimising vaginal delivery blood loss.

Key words: PPH