METHYLATION OF PROLACTIN AND OXYTOCIN HORMONE GENES; PHYSIOLOGICAL FUNCTIONS AND ROLES IN DISEASE STATES

Main Article Content

Manoj G Tyagi Deepak G Shewade Megha Chaudhary Mohammed I Wani Shyam S Yadav

Abstract

DNA methylation is the key mechanism in epigenetic events involved in gene silencing and gene genome stability. The two important hormones involved in social behaviour, lactation and parturition are Oxytocin and Prolactin. There is growing interest in epigenetic modification of oxytocin and prolactin in neurotransmission interaction and their functional significance. This review outlines the influence of DNA methylation of genes of oxytocin and prolactin hormones/receptors and impact on their biological roles and influence on endocrine function in mammals.


Keywords: Prolactin, Oxytocin, receptor, DNA methylation, epigenetics

Article Details

How to Cite
Tyagi, M. G., Shewade, D. G., Chaudhary, M., Wani, M. I., & Yadav, S. S. (2019). METHYLATION OF PROLACTIN AND OXYTOCIN HORMONE GENES; PHYSIOLOGICAL FUNCTIONS AND ROLES IN DISEASE STATES. Journal of Biomedical and Pharmaceutical Research, 8(2). https://doi.org/https://doi.org/10.32553/jbpr.v8i2.584
Section
Research Articles