METHYLATION OF PROLACTIN AND OXYTOCIN HORMONE GENES; PHYSIOLOGICAL FUNCTIONS AND ROLES IN DISEASE STATES

  • Manoj G Tyagi College of Paramedical Technology NIMS University, Jaipur Rajasthan 313021
  • Deepak G Shewade Jaipur, Rajasthan and Department of Pharmacology
  • Megha Chaudhary JIPMER Pondicherry
  • Mohammed I Wani JIPMER Pondicherry
  • Shyam S Yadav JIPMER Pondicherry
DOI: https://doi.org/10.32553/jbpr.v8i2.584

Abstract

DNA methylation is the key mechanism in epigenetic events involved in gene silencing and gene genome stability. The two important hormones involved in social behaviour, lactation and parturition are Oxytocin and Prolactin. There is growing interest in epigenetic modification of oxytocin and prolactin in neurotransmission interaction and their functional significance. This review outlines the influence of DNA methylation of genes of oxytocin and prolactin hormones/receptors and impact on their biological roles and influence on endocrine function in mammals.

Keywords: Prolactin, Oxytocin, receptor, DNA methylation, epigenetics

Published
2019-04-28
How to Cite
Tyagi, M. G., Shewade, D. G., Chaudhary, M., Wani, M. I., & Yadav, S. S. (2019). METHYLATION OF PROLACTIN AND OXYTOCIN HORMONE GENES; PHYSIOLOGICAL FUNCTIONS AND ROLES IN DISEASE STATES. Journal of Biomedical and Pharmaceutical Research, 8(2), 01-07. https://doi.org/10.32553/jbpr.v8i2.584
Issue
Vol. 8 No. 2 (2019)
Section
Research Articles

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