A Smart Review on Rubus Paniculatus in Preclinical Models

Abstract

Rubus Paniculatus Smith. (Family Rosaceae), often known as the yellow Himalayan raspberry (Yellow Hissar), is one of the most widely used edible fruits in Indian folk medicinal systems. The current review aims to identify the gap between research and existing applications of this fruit to help scientists explore the current trends and opportunities for future development. Fruits of R. Paniculatus are the source of several classes of compounds. Fruits of R. Paniculatus are alsorich in nutrients such as carbohydrates, vitamins, and minerals. Fruits of R. Paniculatus have been the subject of several in vitro and in vivo investigations, all of which have corroborated their wide range of biological activities and demonstrated their potential for the identification of new therapeutic candidates and the development of innovative herbal food supplements. Additional mechanism-based pharmacological evaluation and clinical research should provide an adequate scientific basis for the traditional usage of R. Paniculatus fruits, which is currently not sufficiently supported by the available research on its active components and molecular mechanisms. The vast majority of people continue to view medicinal plants as a low-cost source of medications and treatments. Numerous trees, herbs, plants, and shrubs have beenused as remedies for various ailments since the dawn of time. Rubus Paniculatus Smith, a weedy wild raspberry that flourishes in damp woods at high elevations, particularly those in the Himalayas and the Nilgiris area, is one of the important ethnomedicinal plants in the genus Rubus. Traditional Tibetan medicine places a great deal of importance on the plant R. Paniculatus. Because of the abundance and diversity of phenolics and flavonoids in fruits or berries, which have a high concentration of both, they are generally regarded as inherently healthful foods. The roots and leaves, as well as the fruit, have traditionally been used as therapeutic agents for several illnesses including colic pain, gastrointestinal discomfort, wound healing, diarrhea, antifertility, antibacterial, analgesic, epilepsy, and others. Theobjective of the current review is to concentrate on the pharmacological characteristics, nutrition profile, phytoconstituents, and folkloric therapeutic applications of R. Paniculatus, therefore achieving the review's overall subject.

KEYWORDS: Paniculatus, Himalayan raspberry, Numerous trees, Raspberry, carbohydrates, Cheeseberry.