Study of effect of solubility of a sparingly water soluble drug in presence of surfactant

  • Ashish Kumar Gupta1*, Amita Tilak, Sudhir Singh Gangwar, Minakshi Verma *Department of pharmacy, V.B.S.Purvanchal University, Jaunpur Department of pharmacy, G.S.V.M. Medical College, Kanpur

Abstract

Solubility plays an important role in dissolution and absorption of drug. Benzoic acid has less solubility in aqueous media. The aim of present study was to study the effect of solubility enhancing agents at room temperature on the solubility of benzoic acid. Sodium Lauryl Sulphate (SLS) in various concentrations were used to study the solubility of Benzoic acid in water. The solubility of benzoic acid in water is directly proportional to the concentration of the surfactant added. The solubility of benzoic acid increases with increase in concentration of surfactant.

 

Keywords: Solubility, Benzoic acid, SLS

Published
2016-10-30
How to Cite
Gangwar, Minakshi Verma, A. K. G. A. T. S. S. (2016). Study of effect of solubility of a sparingly water soluble drug in presence of surfactant. Journal of Biomedical and Pharmaceutical Research, 5(5). Retrieved from http://jbpr.in/index.php/jbpr/article/view/131
Issue
Vol. 5 No. 5 (2016)
Section
Research Articles

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