Association between Helicobacter pylori infection and increased risk of typhoid fever in Khartoum- Sudan

Fadwa Hassan Omer Mohammed1*, Wafa Ibrahim Elhag2*,Hamza Abdallha3*, Huda Ali4*

Fadwa Hassan Omer Mohammed1*, Wafa Ibrahim Elhag2*,Hamza Abdallha3*, Huda Ali4* 1*M.SC student Microbiology Department, Faculty of Medical Laboratories Sciences, Al- Neelain University, Sudan 2*Associate Professor, Microbiology Department Faculty of Medical Laboratories Sciences, Al- Neelain University, Sudan

Abstract

Background and objective:

There are some reports on the association between Helicobacter pylori infection and typhoid fever in different parts of the world. This study was carried out to detect Association between Helicobacter pylori infection and increased risk of typhoid fever in Khartoum- Sudan, and to determine the relationship between them and certain factors such as gender, age, and residence.

Material and method:

It was descriptive cross-sectional study conducted from March- May 2015. A total of 90 febrilepatients who attended different hospitals.(36 males and 54 females) were enrolled. Serum specimens were tested by rapid test for typhoid (50% positive as case and 50% negative as control) then were tested by ELISA IgG of Helicobacter pylori. Data was analyzed by chi squared test in SPSS software.

Result:

Seropositivity of Helicobacter IgG was detected among the typhoid patients case group in 84.4% of case subject(38 of 45) and negative was 15.6% of cases(7 of 45). While seropositive of Helicobacter IgGamong control group it was detected in 86.7% (39 of 45) and negative 13.3% (6 of 45).

This study indicated statistically insignificant association between H.pylori and increased risk of typhoid fever in Khartoum –Sudan.

Keywords: Association, Helicobacter pylori, typhoid fever, Rapid test, ELISA, Khartoum -Sudan.