PREVALENCE OF NON-FERMENTING GRAM NEGATIVE BACILLI FROM CLINICAL ISOLATES AND THEIR ANTIBIOGRAM PROFILE

  • Thipperudraswamy T.1*, Sudhindra.K.S2, Shobha Nadigar3, Mahesh Kumar4 1Assistant Professor, Department of Microbiology, Basaveshwara Medical College & Hospital Chitradurga, Karnataka, India 2Associate Professor, Department of Microbiology, Basaveshwara Medical College & Hospital, Chitradurga, Karnataka, India 3Professor and Head, Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India 4Assocate Professor, Department of Microbiology, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India

Abstract

Background and Objectives: Non fermenting gram negative bacilli (NFGNB) are an increasing cause of concern in the hospitals as they produce a therapeutic dilemma for the treating physician.The present study was undertaken to know the prevalence and the resistance pattern of non-fermenting gram negative bacilli from clinical isolates.

Methods: 2758 bacterial isolates 389 (14.1%) were Non-fermenting gram negative bacilli recovered from various clinical specimens. All the samples were processed for routine bacterial culture and antimicrobial susceptibility test as per standard protocol (CLSI guidelines). Results: Among NFGNBs, 274(70.43%) were Pseudomonas aeruginosa, 99 (25.44%) Acinetobactercalcoaciticus-baumaniicomplex, 10 (2.57%) Acinetobacterlwoffiiand6 (1.54%) Acinetobacterhemolyticus. All the Pseudomonas aeruginosa isolates were sensitive to Polymyxin B and least resistance was observed towards Amikacin 9.85%.All the Acinetobacterisolates were sensitive to Polymyxin B. Only 20.20 % of Acinetobactercalcoaciticusbaumannii complex were resistant to Imipenemwhereas rest all strains were sensitive. Conclusion: The prevalence of NFGNB among clinical isolates was 14.1%. Significantly higher resistance rate was observed by these isolates to almost all the drugs routinely used.

Keywords: NFGNB, Pseudomonas, Acinetobacter, Amikacin, Polymyxin B

Published
2014-04-29
How to Cite
Shobha Nadigar3, Mahesh Kumar4T. T. S. (2014). PREVALENCE OF NON-FERMENTING GRAM NEGATIVE BACILLI FROM CLINICAL ISOLATES AND THEIR ANTIBIOGRAM PROFILE. Journal of Biomedical and Pharmaceutical Research, 3(2). Retrieved from http://jbpr.in/index.php/jbpr/article/view/260
Issue
Vol. 3 No. 2 (2014)
Section
Research Articles

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