Formulation and Evaluation of Pluronic lecithin organogel of Flurbiprofen

Abstract

The aim of the present work was to generate an index to predict topical ef®ciency of a series of nonsteroidal anti-in¯ammatory drugs Organogel, a viscoelastic system, can be regarded as a semi-solid preparation which has an immobilized external apolar phase. The apolar phase gets immobilized within spaces of the three-dimensional networked structure formed due to the physical interactions amongst the selfassembled structures of compounds regarded as gelators.  In general, organogels are thermodynamically stable in nature and have been explored as matrices for the delivery of bioactive agents. In the current manuscript, attempts have been made to understand the properties of organogels, various types of organogelators and some applications of the organogels in controlled delivery.

KEYWORDS: Organogel, Gel, Gelator, Drug delivery, Biocompatibility