Application of omics in personalized oral health care: A paradigm shift

Abstract

Periodontal disease and Dental caries are the most common oral diseases in adult populations worldwide and is a major public health concern due to its substantial cost to the oral health care system. During recent years a significant amount of evidence has been produced on the pathogenesis and risk factors of oral disease and its association with systemic diseases and general health. Personalized   medicine is an emerging field within health care that uses an individual’s genomic information and its resulting products RNA, proteins and metabolites to customize care that is specific to that individual. Customized oral health care is cost effective individualized strategies for oral diseases. The goals of Customized oral health care are to determine a person’s susceptibility or risk of developing disease, establishing a diagnosis, determining disease patterns and prognosis, determining appropriate interventions, predicting and monitoring therapeutic response, and predicting an individual’s response to environmental and microbial challenges. This review highlights the holistic approach to improve oral health care.

Keywords: Customized, Genetics, Microbiomics, Personalized medicine