Solubility Enhancement of Antihyperlipidemic Drug by Solvent Diffusion Technique
Abstract
Poor aqueous solubility of drugs is major limiting factor with many new drugs in their successful launch in market in spite of their potential pharmacokinetic activity. Therefore, poor solubility is critical factor if the molecule is to survive the pharmaceutical development process. In the current work, it was planned to enhance the solubility of antihyperlipidemic drug by solvent diffusion technique. For this the drug clofibrate and excipients were procured and spherical agglomerates were prepared and evaluated. The findings of the study states the novelty the hypothesis.
Keywords: Solubility, Diffusion, Agglomerates
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