An Assessment of Invitro Anti-Alzheimer Activity of Ammania Bacciferra Linn.
Abstract
Neurodegenerative disorders are characterized by the progressive and irreversible loss of neurons from specific brain areas. Alzheimer's disease (AD), where loss of hippocampal and cortical neurons impairs memory and cognitive function. From the literature review it was revealed that Ammania bacciferra linn. possess good antioxidant activity because of its active constituents and anti-oxidant may treat some neurodegenerative disorders. The main objective of this work is to identify the Alzheimer activity of Ammania bacciferra linn. Invitro activity was performed by Ellman method and IC50 Value was found to be 315 µg/mL Further extract was subjected for in vivo activity.
Keywords: Neurodegenerative disorders, neurons, Alzheimer's diseases. Memory enhancer.
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