Characteristics of liposome used for drug delivery system

Abstract

Liposome as a drug delivery system is emerges as a one of the potential in pharmaceutical industries. The properties of nano-medicines such as release from dosage forms at specific sites as well as drug circulation and absorption into body membranes are dramatically affected by some physical and chemical characteristics of liposome as a drug delivery system. Zeta potential is a scientific term used for electro kinetic potential in colloidal systems which has a major effect on the various properties of liposome. There are various challenges in the field of drug delivery system, including poor solubility and stability. Presently, colloidal nano-carriers are emerges as a potential drug delivery system. Furthermore, they show an unlimited capacity in the field of drug targeting. Particle size and charge are two major factors which could play key roles in this regard. In this paper synthesis of liposome by extrusion method and  the effect of zeta potential and particle size are considered.

 Keywords: Nano-drug delivery, Zeta potential, Drug targeting, Particle size, Particle charge