OPTIMUM DESIGN AND ANALYSIS OF RECTANGULAR MICROCANTILEVER FOR HUMAN IMMUNODEFICIENCY VIRUS DETECTION

Abstract

Microcantilever based sensors is a promising platform for sensors in various chemical and biological applications. Rectangular microcantilever is commonly used biosensing device for the detection of various disease detection target in biomedical applications .HIV is a virus which producing life threatening diseases which attacks the immune system. In this paper to detect HIV, various analyses performed on rectangular cantilever for optimum design to produces maximum total displacement due to attachment of HIV virus on the surface of the microcantilever.  This study proposes a rectangular cantilever for the detection of HIV under static mode of operation. The analysis is performed by varying the length, width, thickness of the rectangular cantilever for getting maximum displacement for one HIV detection. The simulation results show the displacement of cantilever with number of HIV targeted on the cantilever.  From this analysis rectangular cantilever with length 1000 µm, width 100 µm and thickness 0.5 µm produces maximum deflection of 1.632 x10^-8 µm with respect to the force applied due to one virus of HIV.  Hence it may be possible to detect the HIV virus in human by using proposed rectangular microcantilever sensor as it produces measurable deflection using recent read out methods.

Key words: Rectangular Microcantilever, Static mode of operation, HIV detection, Simulation