A REVIEW ON SOLID SELF EMULSIFYING DRUG DELIVERY SYSTEM
Abstract
Self-emulsifying drug delivery system (SEDDS) is one of the most popular and commercially viable formulation approaches for enhancing solubility of poorly water soluble drugs. SEDDS are isotropic mixtures of oil, surfactant and co-surfactant which are generally present in liquid or semisolid form. Solid SEDDS are solid forms of liquid SEDDS converted into solid by suitable means. These solid SEDDS are considered more stable over liquid SEDDS, also solid forms improve handling, packaging and storage. The aim of this review is to discuss various methods of preparation of solid SEDDS and different existing drug delivery systems which incorporated solid SEDDS to obtain advantage of both the systems.
KEYWORDS: self-emulsifying, microsphere, liposphere, nanoparticles, implants, SEDDS
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