Antimicrobial Resistance Pattern of Acinetobacter Baumannii Infection: A Comparative Study in Indoor and Outdoor Patients.

*Sujata Singh (MD)1, Rahul Goyal (MD)2, N A Ansari (MD)3, Rashmi Singh (MD)4,

*Sujata Singh (MD)1, Rahul Goyal (MD)2, N A Ansari (MD)3, Rashmi Singh (MD)4, 1Associate Professor, Department of Pharmacology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly -243 202, U.P., India. 2Associate Professor, Department of Microbiology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly -243 202, U.P., India 3Professor & Head, Department of Pharmacology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly -243 202, U.P., India 4Assistant Professor, Department of Pharmacology, Rohilkhand medical college and hospital, Bareilly -243 202, U.P., India.

Abstract

Acinetobacter baumannii is a ubiquitous pathogen that has emerged in the last few decades as a major cause of healthcare-associated infections and nosocomial outbreaks. Increasing antimicrobial resistance has been documented in the past few decades. Multidrug-resistant Acinetobacter baumannii is recognized to be among the most difficult antimicrobial-resistant gram-negative bacilli to control and treat. This retrospective study was planned to study the incidence of Acinobacter baumannii infection and the antimicrobial resistance pattern among the indoor and outdoor patients. Out of a total of 6315 infected samples,1004 were positive for Acinetobacter baumannii. Isolation was maximum in pus, followed by sputum and endotracheal tube aspirate. When antibiotic susceptibility was examined, the highest susceptibility was to Imepenam in the outpatients and to Imepenam and Nitrofurantoin in the inpatients. The result also demonstrates that the inpatients samples were more resistant to antibiotics as compared to outpatients. This emphasizes the need for periodical surveillance studies.

KEY WORDS: Antimicrobial resistance, Acinetobacter baumannii, indoor patients, outdoor patients