A Review on Nanocochleate – A Novel Lipid Based Drug Delivery System.

Abstract

Nanaocochleate  represent  a  new  approach   for  oral  and  systemic  delivery  of  drugs .  It is a novel lipid-based system which is suitable for the oral and systemic administration of a wide variety of molecules with important therapeutic activities, including drugs, genes, and vaccine antigens. This novel formulation approach is applicable to macromolecules as well as small molecule drugs that are hydrophobic and that possess poor oral bioavailability. Studies for oral delivery of clinically important drugs are being carried out in suitable animal models to evaluate their efficacy.

KEYWORDS: Phospholipids, Liposomes, Cochleates.